Supplementation with aqueous leaf extract of Morinda lucida enhances immunorestoration and upregulates the expression of cytokines and immunostimulatory markers. The study was designed to obtain information on febrile illnesses and herbal remedies for treatment with the aim of identifying potential antimalarial drugs. The isolation and detection of alkaloids content of Morinda lucida Ezeogwu from rubiceae family, a medicinal plant was carried out using solvent-extraction process. The simple quantitative analysis of the extract was based on the intensity of the colour change. Many compounds are excluded from the group because it is simply practical to do so; purines, pyrimidine, pyrazine, vitamins, antibiotics and amino sugars are all excluded.
Dyes and Tannins, Jansen, P. We also reported the antihyperglycaemic activity of the crude ethanolic leaf extract of Morinda lucida in normal and alloxan-induced hyperglycaemic rats The plant was identified by taxonomists at the Botany Department University of Ghana who identified the correct species. It will also help us to know if any of their constituents will be extracted and used in other sphere of human endeavour like the chemical industries, cosmetics, specialty food and insecticidal industries. All treatments lasted 14 days after which the fasting blood glucose was determined Bioassays: J Med Food Apr;13 2: By the 5th day, rats with fasting blood glucose of equal or greater than mg dL -1 were considered hyperglycaemic.
Tetraoxosulphate VI acid was added to form a layer and the colour at interphase recorded. Preliminary phytochemical tests carried out on the leaves of Morinda lucida indicated the presence of saponins, anthraquinones, cardenolides, alkaloids, sterols and tannins. Anti-malarial synergy of secondary metabolites from Morinda lucida Benth. Results obtained on the antibacterial activity of the crude M.
This project work is aimed at isolating of alkaloidal content of Morinda lucida a medicinal plant and detecting it with some diodal. The leaves and stem bark of Morinda lucida are used as purgative, emetic and diuretic 7.
ISOLATION OF ALKALOIDS FROM A MEDICINAL PLANT (MORINDA LUCIDA)
Antimicrobial activity of Morinda lucida on test lucida leaf may be indicative of the organisms. Thus targeting HDACs with inhibitors is a major focus in anticancer drug research.
This was then followed by the following treatments:. Alloxan, like its counterpart, streptozotocin has been frequently used to induce either type 1 or type 2 diabetes The Rf values were calculated for all the spots.
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Ivermectin, the current drug of choice is only microfilaricidal and suboptimal response to it is increasingly being reported. It also validates its application as a plant used in traditional medicine. Anticoccidial effects of Morinda lucida acetone extracts on broiler chickens naturally infected with Eimeria species.
Plant identification and authentication has earlier been done. Acute oral toxicity test was performed to determine the LD 50 ; sub-chronic toxicity study was then carried out by oral administration of different doses of the extract on daily basis to different groups of rats for 42 days. Click here to sign up. The research work is important because it will help to know the alkaloidal content of this medicinal plant Morinda lucida leaves.
The management of blood glucose level is the hallmark in the litrrature of this disease. The project work was limited only to isolating and literture of alkaloidal content of Morinda lucida a medicinal plant using solvent because of high cost of spectroscopic instrument like UV, IR and NMR as these would have help in further analysis of the extracted alkaloid. This necessitates chemotherapeutic control alternatives, and plant secondary metabolities with activity is one of those potential solutions.
Morinda lucida Publications | PubFacts
According to Rogers M. The insecticidal activity was compared omrinda two pesticides, Phostoxin and Primo-ban By the 5th day, rats with fasting blood glucose of equal or greater than mg dL -1 were considered hyperglycaemic. Medicinal Plants and Traditional Medicine in Africa.
Epub Aug Biomed Res Int 24; To investigate the effect of Morinda lucida Benth Rubiaceae on the reproductive activity of male albino rats.
Mutagenic screening of some commonly used medicinal plants in Nigeria.
Rubiacae is used in traditional medicine in many West African countries for the treatment of various human diseases. Leishmaniasis is an infectious disease transmitted by the sand fly. J Ethnopharmacol Sep 7; 3: A total of nine components were isolated from Morinda lucida using a solvent system containing hexane and ethyl acetate 2: Thus, they can be used in the treatment of infectious diseases caused by morindaa resistant microbes.
Structured questionnaires were used to explore the ethnobotanical practices amongst the traditional healers. It is caused by over 20 different species of Leishmania and has affected over 14 million people worldwide. Comparative toxicity of alloxan, N-alkyl-alloxans and ninhydrin to isolated pancreatic islets in vitro.